Research

We are releasing qradiomics — an open-source Python CLI that unifies more than a decade of Choi Lab radiomics work into a single, reproducible, pip-installable toolkit. What is qradiomics? qradiomics (command: qr) is a radiomics research CLI built for the full data flow from raw DICOM to published-grade results: DICOM download → conversion → feature extraction → clinical merge → modeling Each step is a single Unix-style command. Pipelines are assembled from those atomic commands using plain JSON plans, executed by Nextflow (per-patient parallel), Prefect, or inline. One command gets you started: ...

Thrilled to share that our work has been selected for an Oral Scientific Presentation in the BEST of Physics session at the American Society for Radiation Oncology (ASTRO) 2026 Annual Meeting, September 26–30 in Boston, MA. Out of ~2,700 abstracts submitted to ASTRO this year, only 300 were chosen for oral presentation, and BEST of Physics gathers the highest-rated physics work of the meeting. Presentation details Abstract # 75557 Title Early Adaptive Interventions in Lung Cancer: Leveraging Fusion of Longitudinal CBCT Trajectories and Clinical Variables for Robust Survival Prediction Session SS 19 — BEST of Physics Date / Time September 28, 2026 · 10:45 AM – 12:00 PM ET Venue Thomas M. Menino Convention & Exhibition Center, Boston, MA Format 7-min oral + 3-min Q&A Publication Red Journal supplement Authors Wookjin Choi, Pradeep Bhetwal, Michael Dichmann, Yingcui Jia, Wenchao Cao, Danfu Liang, Yingxuan Chen, Adam Dicker, Yevgeniy Vinogradskiy ...

License: MIT · Python: 3.11+ · Version: 0.9.0 · Repo: choilab-jefferson/qradiomics Active successor for three earlier Choi Lab radiomics codebases. The C++/MATLAB pipelines in taznux/radiomics-tools, taznux/lung-image-analysis, and choilab-jefferson/LungCancerScreeningRadiomics are superseded by this repo. The feature extractors are now in qradiomics.feature.rtools (Python ITK port, numerically exact to the C++ binary). New work should land here. Radiomics research CLI. qr does two things equally well: Atomic tasks — convert DICOM, extract features, merge clinical, fit a model. Each is a single command, files in / files out. Workflow assembly — generate, mutate, scaffold, and run multi-step pipelines from those atomic tasks. Default executor is Nextflow (per-patient parallel + cache + HPC); Prefect is the secondary executor; inline is the small-cohort fallback. The canonical radiomics data flow has four stages — data → image → features → modeling — and one qr workflow plan call instantiates the whole chain: ...

https://datascience.nih.gov/tools-and-analytics/quantum-computing-new-frontiers-biomedical-research-innovation-lab Last December, I had the incredible opportunity to be part of something truly special. The NIH Office of Data Science Strategy (ODSS) and the National Cancer Institute (NCI) gathered 27 of us from wildly different fields for a five-day Innovation Lab. The goal? To answer a question that sounds like science fiction: How can quantum computing solve today’s most complex biomedical challenges? The room buzzed with a vibrant mix of quantum physicists, computer scientists (both quantum and traditional computing), computational physicists, computational biologists, data scientists, and biomedical researchers. For five intense days, we were immersed in a whirlwind of collaboration, brainstorming, and problem-solving. The energy was electric as we united to bridge the gap between our disciplines and forge new paths for the future of medicine. ...

I’m excited to share a new collaborative study I had the privilege of co-authoring, which was recently published in Nutrients. Led by Jefferson medical student Julia Logan, this work explores how large language models (LLMs) like ChatGPT and Gemini can deliver accessible, culturally sensitive dietary advice to cancer patients—many of whom lack access to professional nutritional counseling due to insurance limitations or socioeconomic barriers. ...

We’re excited to share our latest work published in Technology in Cancer Research & Treatment: “Deep Learning-Based Auto-Segmentation for Liver Yttrium-90 Selective Internal Radiation Therapy” — a collaboration between Jun Li, Rani Anne, and myself. This study introduces a deep learning (DL) model built on the 3D U-Net architecture, developed to automatically segment the liver in CT scans for patients undergoing Y-90 Selective Internal Radiation Therapy (SIRT). Accurate liver segmentation is a critical step for calculating Y-90 dosage, traditionally done manually — a time-consuming and subjective process. ...

Jefferson Investigates: Artificial Intelligence and Heart Disease — The Nexus https://medicalxpress.com/news/2024-06-machine-lung-cancer-scans-heart.html

Our study on cardiac toxicity in lung cancer treatment is now featured in a JCO CCI editorial. Discoveries that could change patient care are on the horizon. Stay tuned! #CardiacToxicity#LungCancer#Innovation Shining a Light: Unveiling Cardiac Risks Using Positron Emission Tomography Imaging in Lung Cancer Radiotherapy

Maria Thor 1,4, Kelly Fitzgerald 2,4, Aditya Apte 1, Jung Hun Oh 1, Aditi Iyer 1, Otasowie Odiase 2, Saad Nadeem 1, Ellen D. Yorke 1, Jamie Chaft 3, Abraham J. Wu 2, Michael Offin 3, Charles B Simone II 2, Isabel Preeshagul 3, Daphna Y. Gelblum 2, Daniel Gomez 2, Joseph O. Deasy 1, Andreas Rimner 2 1Department of Medical Physics, Memorial Sloan Kettering Cancer Center 2Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center 3Department of Medicine, Memorial Sloan Kettering Cancer Center ...

AAPM 2023, ASTRO 2023